1: NaOD / D2O; CH3OD / 24 h / 60 °C 2: NaBH4 / 0.5 h / Ambient temperature View Scheme

sodium tetrahydroborate 0.5 h; Ambient temperature;

in ethanol T=37°C; 1 h; NADPH, glucose 6-phosphate, dithiothreitol, glucose-6-phosphate dehydrogenase, tris-malate buffer pH 7.2, microsomal placental aromatase, 1M NaOH, air; also at pH 6.5 or in the presence of bovine albumin instead of the aromatase; Product distributionMechanism;