3,6-二碘 (1H)吲唑合成路线 （共 2 条）
反应条件
1: With sodium hydrogensulfite in water; N,N-dimethyl-formamide T=0°C; 0.5 h; 2: With potassium hydroxide in water; N,N-dimethyl-formamide 0.5 h; 3: With iodine in water; N,N-dimethyl-formamide 0.5 h;
参考文献
WO2006/48745 A1, ;
Page/Page column 29 ;
WO 2006/048745 A1
反应条件
cesium hydroxide; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris-(dibenzylideneacetone)dipalladium(0) in N,N-dimethyl-formamide
T=70°C; 0.5 h;
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2006/94881 A1, 2006 ;
Location in patent: Page/Page column 21; 22 ;
US 20060094881 A1
