3-吡咯烷-1-甲酸苄酯合成路线 (共 23 条)
反应条件
sodium hydroxide; sodium tetrahydroborate; dihydrogen peroxide; (Ipc)2BH 1.) 0 deg C, 4 h; 2.) 25 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brown, Herbert C.; Prasad, J. V. N. Vara
Journal of the American Chemical Society, 1986 , vol. 108, # 8 p. 2049 - 2054
反应条件
1: Rh2(OAc)4 / CH2Cl2
2: NaOH / methanol
View Scheme
参考文献
Renslo, Adam R.; Jaishankar, Priyadarshini; Venkatachalam, Revathy; Hackbarth, Corinne; Lopez, Sara; Patel, Dinesh V.; Gordeev, Mikhail F.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 15 p. 5009 - 5024
反应条件
Wilkinson's catalyst in toluene
T=145°C; 0.833333 h; Microwave irradiation;
参考文献
Wegner, Jens; Ley, Steven V.; Kirschning, Andreas; Hansen, Anne-Lene; Montenegro Garcia, Javier; Baxendale, Ian R.
Organic Letters, 2012 , vol. 14, # 3 p. 696 - 699