2-氨基-4-(甲硫基)-丁腈合成路线 (共 10 条)
反应条件
ethanol; ammonia T=80°C;
参考文献
Du Pont de Nemours and Co.
Patent: US2564109 , 1949 ;
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Du Pont de Nemours and Co.
Patent: US2485236 , 1945 ;
反应条件
diethyl ether; ammonium chloride; water
参考文献
Barger; Coyne
Biochemical Journal, 1928 , vol. 22, p. 1423
反应条件
1: Et3N 2: (i) POCl3, Py, (ii) HCl, Et2O View Scheme
参考文献
Kawashiro,K. et al.
Bulletin of the Chemical Society of Japan, 1977 , vol. 50, p. 2956 - 2960
反应条件
ammonia; ammonium chloride
参考文献
Holland; Nayler
Journal of the Chemical Society, 1952 , p. 3403,3407
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Am. Cyanamid Co.
Patent: US2732400 , 1953 ;
反应条件
(i) POCl3, Py, (ii) HCl, Et2O; Multistep reaction;
参考文献
Kawashiro,K. et al.
Bulletin of the Chemical Society of Japan, 1977 , vol. 50, p. 2956 - 2960
反应条件
hydrogenchloride; 2-methyl-propan-1-ol
参考文献
Johnson,H.E.; Crosby,D.G.
Journal of Organic Chemistry, 1962 , vol. 27, p. 798 - 802
反应条件
ammonium hydroxide T=8 - 40°C; pH=11.6; KineticsMechanism;
参考文献
Taillades, Jacques
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 1 p. 89 - 100
反应条件
hydrogenchloride DL-methionine;
参考文献
Catch et al.
Journal of the Chemical Society, 1947 , p. 1611
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Pierson; Giella; Tishler
Journal of the American Chemical Society, 1948 , vol. 70, p. 1451
Full Text Show Details
du Pont de Nemours and Co.
Patent: US2432478 , 1945 ;
反应条件
ammonium hydroxide T=8 - 40°C; pH=11.6; KineticsMechanism;
参考文献
Taillades, Jacques
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 1 p. 89 - 100
参考文献
Barger; Coyne
Biochemical Journal, 1928 , vol. 22, p. 1423