1-(5-溴-2-呋喃基)乙酮合成路线 (共 13 条)
反应条件
bromine in 1,4-dioxane; diethyl ether T=0 - 5°C;
参考文献
Boykin, David W.; Tidwell, Richard R.; Wilson, W. David; Ismail, Mohamed A.
Patent: US2005/282853 A1, 2005 ;
Location in patent: Page/Page column 15; 19 ;
反应条件
sodium
toluene, 2) reflux, 5 h; Yield given. Multistep reaction;
参考文献
Sarma; Krishna; Shridhar; Seshagiri; Taneja
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 11 p. 993 - 995
反应条件
tetrabutylammomium bromide; palladium diacetate; potassium carbonate in water
T=70°C; Suzuki Coupling; 3.33 h; Inert atmosphere;
参考文献
Lv, Wei; Banerjee, Biplab; Molland, Katrina L.; Seleem, Mohamed N.; Ghafoor, Adil; Hamed, Maha I.; Wan, Baojie; Franzblau, Scott G.; Mesecar, Andrew D.; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 406 - 418