4-氯-2-三氟甲基苯甲腈合成路线 （共 5 条）
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=80°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/44454 A1, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/044454 A1
反应条件
in N-methyl-acetamide; water
反应条件
formic acid; nickel-aluminum alloy; water T=100°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/44454 A1, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/044454 A1
参考文献
Hauptschein et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 1051,1054
反应条件
18-crown-6 ether; sodium hydride in N,N-dimethyl-formamide
T=140°C; 60 h;
参考文献
Huegel, Helmut M.; Rix, Colin J.; Fleck, Karin
Synlett, 2006 , # 14 p. 2290 - 2292
