2-(间甲氧基苯基)环氧乙烷合成路线 （共 18 条）
反应条件
sodium methylate 1.) CH3CN; Multistep reaction;
参考文献
Ono; Yamafuji; Chaki; Morita; Todo; Maekawa; Kitamura; Tai; Narita
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 9 p. 1488 - 1491
反应条件
in tetrahydrofuran; dimethyl sulfoxide 1.) 0-5 deg C, 15 min., 2.) r.t., 90 min; Yield given;
参考文献
Alvarez; Granados; Lavilla; Salas
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 3 p. 745 - 750
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride 1a) 0 deg C, 15 min, 1b) benzene, 18-20 deg C, few minutes, 2) benzene, 50 deg C, 10 h; Yield given. Multistep reaction;
参考文献
Haridas, K.; Dev, Sukh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1018 - 1020
反应条件
sodium tetrahydroborate in ethanol 2 h; Heating; Yield given. Yields of byproduct given;
参考文献
Ookawa, Atsuhiro; Hiratsuka, Hiroshi; Soai, Kenso
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 1813 - 1818
反应条件
in methanol T=60 - 100°C;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: WO2004/22568 A1, 2004 ;
Location in patent: Page 35 ;
参考文献
Haridas, K.; Dev, Sukh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1018 - 1020
反应条件
[(R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) acetate; water in tetrahydrofuran
T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
[(R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) acetate; water in tetrahydrofuran
T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
