4,5-二甲氧基-3-碘苯甲醛合成路线 （共 11 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100 - 120°C; 5 h;
参考文献
Nimgirawath, Surachai
Australian Journal of Chemistry, 1994 , vol. 47, # 5 p. 957 - 962
反应条件
potassium carbonate in N,N-dimethyl-formamide 20 h;
参考文献
Venter, Daniel P.; Langenhoven, Jan H.
South African Journal of Chemistry, 1996 , vol. 49, # 1-2 p. 40 - 46
反应条件
water; sodium hydrogencarbonate anschliessend Behandeln mit Dimethylsulfat;
参考文献
Journal of Organic Chemistry, , vol. 8, p. 358,363,365
反应条件
potassium carbonate in N-methyl-acetamide
反应条件
1: 3-hydroxy-5-iodo-4-methoxybenzaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=20°C; 0.583333 h; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Nammalwar, Baskar; Bunce, Richard A.; Berlin, K. Darrell; Bourne, Christina R.; Bourne, Philip C.; Barrow, Esther W.; Barrow, William W.
Organic Preparations and Procedures International, 2012 , vol. 44, # 2 p. 146 - 152
反应条件
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.83 h / 20 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.58 h / 20 °C / Inert atmosphere 2.2: 20 °C / Inert atmosphere View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 44, # 2 p. 146 - 152
反应条件
1: aq. NaOH solution / anschliessend mit Jod in wss.KI-Loesung 2: aq. NaOH solution; ethanol View Scheme
参考文献
Svensk Kemisk Tidskrift, , vol. 47, p. 223,227
反应条件
NiCl2((PPh3)P)2; triphenylphosphine; zinc in N,N-dimethyl-formamide T=56°C; 24 h;
参考文献
Whiting, Donald A.; Wood, Andrew F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 623 - 628
反应条件
1: 3,4-dimethoxy-5-iodo-benzaldehyde With di(isobutyl)zinc in 1-methyl-pyrrolidin-2-one; diethyl ether
T=20°C; 3 h;
2: allyl bromide With Li(acac) in 1-methyl-pyrrolidin-2-one; diethyl ether
T=20°C; 5 h;
参考文献
Kneisel, Florian F.; Leuser, Helena; Knochel, Paul
Synthesis, 2005 , # 15 art. no. T08305SS, p. 2625 - 2629
反应条件
1: 76 percent / piperidine / pyridine / 2 h / Heating
2: 60.8 percent / NaOH, CuSO4*5H2O / H2O / 12 h / Heating
3: 96 percent / H2, 10percent NaOH / 10percent Pd/C / ethanol / Ambient temperature
4: 80 percent / K2CO3 / ethanol / 10 h / Heating
View Scheme
参考文献
Nimgirawath, Surachai
Australian Journal of Chemistry, 1994 , vol. 47, # 5 p. 957 - 962
