3-甲基-2-吡啶-2-丁腈合成路线 （共 5 条）
反应条件
sodium hexamethyldisilazane in tetrahydrofuran; toluene T=0 - 20°C;
参考文献
Klapars, Artis; Waldman, Jacob H.; Campos, Kevin R.; Jensen, Mark S.; McLaughlin, Mark; Chung, John Y. L.; Cvetovich, Raymond J.; Chen, Cheng-Yi
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10186 - 10189
反应条件
hydrogen; palladium on activated charcoal in ethanol P=760 Torr; Ambient temperature;
参考文献
Bernhart; Condamine; Demarne; Roncucci; Gagnol; Gautier; Serre
Journal of Medicinal Chemistry, 1983 , vol. 26, # 3 p. 451 - 455
反应条件
1: 89 percent / acetic acid, piperidine / benzene / 135 h / Heating 2: H2 / 5 percent Pd/C / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Bernhart; Condamine; Demarne; Roncucci; Gagnol; Gautier; Serre
Journal of Medicinal Chemistry, 1983 , vol. 26, # 3 p. 451 - 455
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride overnight;
参考文献
Hermann, Christine K. F.; Sachdeva, Yesh P.; Wolfe, James F.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1061 - 1065
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; oxygen in dimethyl sulfoxide 3 h;
参考文献
Donetti, Arturo; Boniardi, Orazio; Ezhaya, Antoine
Synthesis, 1980 , # 12 p. 1009 - 1011
