5-氧代-2,3-二氢-5H-[1,3]噻唑并-[3,2-a]嘧啶-6-羧酸乙酯合成路线 （共 6 条）
反应条件
1: in dichloromethane T=20°C; 4 h; 2: With triethylamine in dichloromethane T=20°C; 16 h;
参考文献
Landreau; Deniaud; Reliquet; Meslin
Synthesis, 2001 , # 13 p. 2015 - 2020
反应条件
tetrabutylammomium bromide; potassium carbonate in benzene T=70°C;
参考文献
Hassan; Mohamed; Shiba; Abou El-Regal; Khalil
Phosphorus, Sulfur and Silicon and the Related Elements, 2003 , vol. 178, # 11 p. 2497 - 2504
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 1527 - 1529
反应条件
formic acid; methanesulfonic acid 5 h; Heating;
参考文献
Shridhar, D. R.; Jogibhukta, M.; Joshi, P. P.; Rao, C. Seshagiri; Junnarkar, A. Y.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 492 - 494
反应条件
1: methanesulphonic acid / formic acid
2: thionyl chloride / 4 h / Heating
3: pyridine / 1.) 0 deg C, 2.) room temperature
View Scheme
参考文献
Shridhar, D. R.; Jogibhukta, M.; Joshi, P. P.; Rao, C. Seshagiri; Junnarkar, A. Y.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 492 - 494
反应条件
1: methanesulphonic acid / formic acid
2: thionyl chloride / 4 h / Heating
3: pyridine / 1.) 0 deg C, 2 h, 2.) room temperature, 4 h
View Scheme
参考文献
Shridhar, D. R.; Jogibhukta, M.; Joshi, P. P.; Rao, C. Seshagiri; Junnarkar, A. Y.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 492 - 494
