Kim, Jihye; Kang, Sookjin; Hong, Sungchae; Yum, Soowhan; Kim, Young Mi; Jung, Yunjin
European Journal of Medicinal Chemistry, 2012 , vol. 48, p. 36 - 44
1.1: sulfuric acid / 120 h / Reflux
2.1: potassium carbonate / acetone / Reflux
3.1: potassium tert-butylate / tetrahydrofuran / 2 h / 0 °C
4.1: sodium tetrahydroborate; methanol / 4 h / 0 - 20 °C
5.1: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 0 - 20 °C
6.1: triphenylphosphine; water / tetrahydrofuran / 50 °C
6.2: 0.08 h / 20 °C
View Scheme
参考文献
PFIZER INC.; AM ENDE, Christopher William; JOHNSON, Douglas Scott; O'DONNELL, Christopher John; PETTERSSON, Martin Youngjin; SUBRAMANYAM, Chakrapani
Patent: WO2011/48525 A1, 2011 ;
WO 2011/048525 A1
PFIZER INC.; AM ENDE, Christopher William; JOHNSON, Douglas Scott; O'DONNELL, Christopher John; PETTERSSON, Martin Youngjin; SUBRAMANYAM, Chakrapani
Patent: WO2011/48525 A1, 2011 ;
WO 2011/048525 A1
Hasse
Chemische Berichte, 1877 , vol. 10, p. 2190
Full Text Show Details
Smith; Peirce
American Chemical Journal, 1879 , vol. 1, p. 176
Chemische Berichte, 1880 , vol. 13, p. 34
