1: 2-bromo-pyridine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; 4 h; Inert atmosphereCooling with ice; 2: With zinc(II) chloride in tetrahydrofuran T=20°C; 2 h; Inert atmosphereCooling with ice; 3: para-chloro-benzonitrile Further stages;
参考文献
Colombe, James R.; Bernhardt, Sebastian; Stathakis, Christos; Buchwald, Stephen L.; Knochel, Paul
Organic Letters, 2013 , vol. 15, # 22 p. 5754 - 5757