3-甲基-2-丙-2-基丁酸合成路线 （共 14 条）
反应条件
lithium diisopropyl amide
参考文献
Dubois, Jacques-Emile; Saumtally, Imran; Lion, Claude
Bulletin de la Societe Chimique de France, 1982 , vol. <2> 2, # 9-10 p. 318 - 320
反应条件
1: C5H8O2(2-)*2Li(1+) With N,N'-dimethyl-N,N'-propyleneurea in tetrahydrofuran T=5°C; 0.5 h; 2: 2-iodo-propane in tetrahydrofuran T=20°C; 2 h;
参考文献
Kaufmann, Dan; Bialer, Meir; Shimshoni, Jakob Avi; Devor, Marshall; Yagen, Boris
Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7236 - 7248
反应条件
sulfuric acid; sodium nitrite
参考文献
Olah,G.A.; Olah,J.A.
Journal of Organic Chemistry, 1965 , vol. 30, p. 2386 - 2387
反应条件
1: aqueous sulfuric acid (96 percent ) / 150 °C 2: sodium nitrite; aqueous sulfuric acid View Scheme
参考文献
Sarel; Newman
Journal of the American Chemical Society, 1956 , vol. 78, p. 5416,5418
Full Text Show Details
Tsai et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 2530
参考文献
Sacks; Aston
Journal of the American Chemical Society, 1951 , vol. 73, p. 3902,3904
反应条件
1: bromine / 0 °C / und Behandeln des Reaktionsprodukts mit Natriummethylat in Aether 2: aqueous hydriodic acid View Scheme
参考文献
Sacks; Aston
Journal of the American Chemical Society, 1951 , vol. 73, p. 3902,3904
反应条件
hydrogenchloride T=160 - 170°C;
参考文献
Traynham; Battiste
Journal of Organic Chemistry, 1957 , vol. 22, p. 1551,1553
反应条件
1: methyl acetate; diethyl ether / -15 °C 2: diethyl ether; water; nitros gas 3: KOH; ethanol View Scheme
参考文献
Marshall
Journal of the Chemical Society, 1930 , p. 2760
Journal of the Chemical Society, 1931 , p. 2338
反应条件
1: KOH; ethanol View Scheme
参考文献
Marshall
Journal of the Chemical Society, 1930 , p. 2760
Journal of the Chemical Society, 1931 , p. 2338
反应条件
1: diethyl ether; water; nitros gas 2: KOH; ethanol View Scheme
参考文献
Marshall
Journal of the Chemical Society, 1930 , p. 2760
Journal of the Chemical Society, 1931 , p. 2338
