1: KOH / ethanol / 0.75 h / 80 °C 2: 2.35 g / aq. HCl / CHCl3; methanol / 1 h / 40 °C 3: 530 mg / pyridine / 0.5 h / 70 °C 4: thallium(III) nitrate trihydrate / CHCl3 / 4 h / 30 °C 5: 218 mg / aq. NaOH / dioxane; methanol / 2 h / 20 °C 6: 96 percent / H2 / Pd/C / methanol; dioxane / 20 °C 7: 85 percent / K2CO3 / acetone / 0.5 h / Heating 8: 91 percent / K2CO3 / acetone / 0.33 h / Heating 9: TsOH*H2O; AcOH / toluene / 0.75 h / 110 °C 10: 95 percent / BCl3 / CH2Cl2 / 0.25 h / 15 °C 11: 66 percent / aq. NaOH / methanol; dioxane / 1 h / 20 °C View Scheme

1: potassium hydroxide / ethanol / 1 h / Heating 2: 5.48 g / aq. HCl / ethanol; CHCl3 / 1 h / 40 °C 3: 88 percent / potassium carbonate / dimethylformamide / 0.5 h / 60 - 70 °C 4: [hydroxy(tosyloxy)iodo]benzene / CHCl3 / 24 h / 20 °C 5: 3.82 g / aq. sodium hydroxide; methanol / CHCl3 / 5 h / 25 °C 6: 91 percent / triethylamine; PPh3; CuI / PdCl2 / dimethylformamide / 2 h / 80 °C 7: 88 percent / hydrogen / palladium on carbon / methanol; dioxane 8: 85 percent / potassium carbonate / acetone / 0.42 h / 45 °C 9: 84 percent / potassium carbonate / acetone / 2 h / Heating 10: 57 percent / p-TsOH hydrate; acetic acid / toluene / 1.5 h / Heating 11: 91 percent / BCl3 / CH2Cl2 / 2.5 h / 20 - 25 °C 12: 72 percent / aq. sodium hydroxide / methanol; dioxane / 0.33 h / 25 °C View Scheme