1: With 18-crown-6 ether; lithium bromide; chiral multisubstituted ferrocene in toluene T=10°C; 456 h; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 0.5 h; Further stages. Title compound not separated from byproducts.;

1: DCC, DMAP / CH2Cl2 2: MsN3, DBU / acetonitrile 3: 4.1 percent / Cu(hfacac)2 / CH2Cl2 / Heating; other catalyst (Rh2(OAc)2; intramolecular metallocarbenoid C-H insertion reaction of indoline diazoamides possessing a C-2 CH2X substituent; site-selectivity, diastereoselectivity, chemoselectivity View Scheme