2,5-二甲基-4-硝基吡唑-3-甲腈合成路线 （共 4 条）
反应条件
potassium iodide in ethanol; water; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile
参考文献
Warner-Lambert Company
Patent: US4666908 A1, 1987 ;
反应条件
potassium iodide in N,N-dimethyl-formamide; acetonitrile 22 h; Heating;
参考文献
Hamilton, Harriet W.; Ortwine, Daniel F.; Worth, Donald F.; Bristol, James A.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 91 - 96
反应条件
sulfuric acid in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
Byk Gulden Lomberg Chemische Fabrik GmbH
Patent: US4317823 A1, 1982 ;
反应条件
sodium methylate
Heating;
参考文献
DeWald; Beeson; Hershenson; Wise; Downs; Heffner; Coughenour; Pugsley
Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 454 - 461
