(R)-2-(2-溴苯基)-4-异丙基-4,5-二氢噁唑合成路线 (共 3 条)
反应条件
1: With N-(chloromethylene)-N-methylmethanaminium chloride in pyridine T=20°C; 2 h; 2: With N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 3 h; 3: With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran Heating; Further stages.;
参考文献
Wuts; Northuis; Kwan
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9223 - 9225
反应条件
1: Et3N / CH2Cl2 2: SOCl2 / CH2Cl2 View Scheme
参考文献
Campbell Bourland; Carter, Rich G.; Yokochi, Alexandre F. T.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 9 p. 1315 - 1329
反应条件
1: Et3N / CH2Cl2 2: SOCl2 / CH2Cl2 View Scheme
参考文献
Campbell Bourland; Carter, Rich G.; Yokochi, Alexandre F. T.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 9 p. 1315 - 1329