1,4-二甲氧基-2-甲基-5-硝基苯合成路线 （共 13 条）
反应条件
nitrogen(IV) oxide in dichloromethane in the dark; -78 deg C, 2 min; RT, 15 min;
参考文献
Rathore; Bosch; Kochi
Tetrahedron, 1994 , vol. 50, # 23 p. 6727 - 6758
反应条件
nitric acid; acetic acid T=45°C;
参考文献
Gilman et al.
Journal of the American Chemical Society, 1944 , vol. 66, p. 798,800
反应条件
nitric acid in water T=0°C; 0.666667 h;
参考文献
Malesani, Giorgio; Galiano, Fabio; Ferlin, Maria Grazia; Masiero, Sergio
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 563 - 569
反应条件
2: 100 percent / NO2 / CH2Cl2 / in the dark; -78 deg C, 2 min; RT, 15 min View Scheme
参考文献
Erdtman
Proceedings of the Royal Society of London, Series A: Mathematical, Physical and Engineering Sciences, 1934 , vol. 143, p. 196,197
Chem. Zentralbl., 1934 , vol. 105, # I p. 3054
反应条件
nitric acid in acetic acid
参考文献
Nakao,H. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1968 - 1979
反应条件
nitric acid in acetic acid
参考文献
Nakao,H. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1968 - 1979
反应条件
1: aq. NaBH4 2: (i) SOCl2, benzene, (ii) /BRN= 3592982/, MeOH 3: HNO3 / acetic acid View Scheme
参考文献
Nakao,H. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1968 - 1979
反应条件
1: (i) SOCl2, benzene, (ii) /BRN= 3592982/, MeOH 2: HNO3 / acetic acid View Scheme
参考文献
Nakao,H. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1968 - 1979
反应条件
quinoline; sodium hydroxide; copper 1.) ethanol, water, reflux, 10 min, RT, 4 h; 2.) 240 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Azadi-Ardakani, Manouchehr; Wallace, Timothy W.
Tetrahedron, 1988 , vol. 44, # 18 p. 5939 - 5952
参考文献
Takada; Ohki
Chemical and Pharmaceutical Bulletin, 1973 , vol. 21, # 6 p. 1369 - 1372
