1,3-二氢-1,1-二甲基-2,1-苯并氧硅杂环戊二烯合成路线 （共 95 条）
反应条件
1: (t-Bu)3P / Pt(1,3-divinyl-1,1,3,3-tetramethyldisiloxane) / hexane / 4 h / 20 °C
2: K2CO3 / methanol; H2O / 24 h / 50 °C
3: 62 percent / K2CO3 / PdCl2; tri(2-furyl)phosphine / dimethylsulfoxide / 21 h / 35 °C
View Scheme
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Chen, Jinshui; Yada, Akira; Hiyama, Tamejiro
Journal of Organometallic Chemistry, 2007 , vol. 692, # 1-3 p. 585 - 603
反应条件
1: o-bromobenzyloxypentamethyldisilane With lithium in diethyl ether
2 h;
2: in diethyl ether
0.833333 h;
3: cyclohexenon in diethyl ether
T=-80 - 20°C; 21 h;
参考文献
Hudrlik, Paul F.; Arango, Jose O.; Hijji, Yousef M.; Okoro, Cosmas O.; Hudrlik, Anne M.
Canadian Journal of Chemistry, 2000 , vol. 78, # 11 p. 1421 - 1427
反应条件
1: o-pentamethyldisilylbenzyl alcohol With methyllithium in tetrahydrofuran
2: benzyl bromide in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; 14 h;
参考文献
Hudrlik, Paul F.; Arango, Jose O.; Hijji, Yousef M.; Okoro, Cosmas O.; Hudrlik, Anne M.
Canadian Journal of Chemistry, 2000 , vol. 78, # 11 p. 1421 - 1427
反应条件
tert.-butyl lithium; ethylene dibromide in tetrahydrofuran
0.5 h;
参考文献
Hudrlik, Paul F.; Arango, Jose O.; Hijji, Yousef M.; Okoro, Cosmas O.; Hudrlik, Anne M.
Canadian Journal of Chemistry, 2000 , vol. 78, # 11 p. 1421 - 1427
反应条件
in tetrahydrofuran; diethyl ether
T=0 - 20°C;
参考文献
Nakao, Yoshiaki; Takeda, Masahide; Matsumoto, Takuya; Hiyama, Tamejiro
Angewandte Chemie - International Edition, 2010 , vol. 49, # 26 p. 4447 - 4450
反应条件
1: in tetrahydrofuran; diethyl ether
T=-78 - 20°C;
2: With water; ammonium chloride in tetrahydrofuran; diethyl ether
T=0°C; Product distribution / selectivity;
参考文献
Nakao, Yoshiaki; Hiyama, Tamejiro
Patent: US2009/69577 A1, 2009 ;
Location in patent: Page/Page column 15 ;
反应条件
in tetrahydrofuran; diethyl ether
T=-78 - 20°C;
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Sahoo, Akhila K.; Yada, Akira; Hiyama, Tamejiro
Journal of the American Chemical Society, 2005 , vol. 127, # 19 p. 6952 - 6953
参考文献
Marcuccio, Sebastian M.; Epa, Ruwan; Moslmani, Maisa; Hughes, Andrew B.
Tetrahedron Letters, 2011 , vol. 52, # 52 p. 7178 - 7181
反应条件
in tetrahydrofuran; diethyl ether
T=-78 - 20°C;
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Sahoo, Akhila K.; Yada, Akira; Hiyama, Tamejiro
Journal of the American Chemical Society, 2005 , vol. 127, # 19 p. 6952 - 6953
反应条件
in tetrahydrofuran; diethyl ether
T=-78 - 20°C;
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Sahoo, Akhila K.; Yada, Akira; Hiyama, Tamejiro
Journal of the American Chemical Society, 2005 , vol. 127, # 19 p. 6952 - 6953
