n-butyllithium in tetrahydrofuran; hexane

n-butyllithium in toluene

n-butyllithium in toluene

1: (1-Ad)2P(O)H With cupric triflate; 1,1,3,3-tetramethyldisiloxane in toluene T=100°C; 9 h; Inert atmosphere; 2: With cesium hydroxide monohydrate in N,N-dimethyl-formamide; toluene T=20°C; 1 h; Inert atmosphereMolecular sieve; 3: 1-iodo-butane in N,N-dimethyl-formamide; toluene T=100°C; 24 h; Inert atmosphereMolecular sieve;

1: in anhydrous butyl ether T=130°C; 8 h; 2: With triethylamine in anhydrous butyl ether T=-78°C; 5 h;

in tetrahydrofuran; hexane Alkylation; 1 h; Heating;

potassium carbonate; palladium diacetate

hydrogenchloride; Zinc chloride; palladium diacetate in tetrahydrofuran