L-天冬氨酸二甲酯盐酸盐合成路线 （共 14 条）
反应条件
1: With water; sodium carbonate in 1,4-dioxane T=5 - 20°C; Cooling with ice; 2: With hydrogenchloride in 1,4-dioxane; water
参考文献
VALORISATION-RECHERCHE SOCIETE EN COMMANDITE; LUBELL, William; JAMIESON, Andrew; BOUTARD, Nicolas; RONGA, Luisa; ST-CYR, Daniel; TURCOTTE, Daniel; CHEN, Wang
Patent: WO2010/105367 A1, 2010 ;
Location in patent: Page/Page column 35; 36; 37 ;
反应条件
water in ethanol T=70°C; 2 h;
参考文献
Gmeiner; Feldman; Chu-Moyer; Rapoport
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3068 - 3074
反应条件
1: With dicyclohexyl-carbodiimide in tetrahydrofuran T=-10 - 5°C; 2: With acetic acid in tetrahydrofuran T=20°C; 0.5 h;
参考文献
Deutsches Krebsforschungszentrum Stiftung des oeffentlichen Rechts
Patent: EP1647283 A1, 2006 ;
Location in patent: Page/Page column 5-6 ;
反应条件
triethylamine in dichloromethane
0.75 h;
参考文献
Coutrot, Ph.; Grison, C.; Charbonnier-Gerardin, C.
Tetrahedron, 1992 , vol. 48, # 45 p. 9841 - 9868
