反应条件
1: 1.) mercuric acetate, 2.) aq. NaOH, NaBH4 / 1.) THF, H2O, RT, 1 h, 2.) THF, H2O, RT, 30 min 2: 84 percent / diethylamine, CuI, bis<triphenylphosphine>palladium(II) acetate / dimethylformamide / 1.5 h / Ambient temperature 3: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 21 h / Ambient temperature 4: 90 percent / H2, quinoline / Lindlar catalyst / methanol; hexane / 0.33 h 5: acetone-d6 / 80.3 °C / var. temp.; kinetics, E(a), ΔG(excit.), ΔH(excit.), ΔS(excit.) View Scheme
参考文献
Journal of the American Chemical Society, , vol. 113, # 18 p. 6958 - 6966
