(4S)-2,2-二甲基-1,3-二氧戊环-4-乙醛合成路线 （共 25 条）
反应条件
1: 77 percent / LiAlH4 / tetrahydrofuran / 5 h / Ambient temperature 2: BF3*Et2O / diethyl ether / 3 h / Ambient temperature 3: 48.3 percent / CrO3 / pyridine; CH2Cl2 / 1.) 0 deg C, 20 min, 2.) 23 deg C, 20 min View Scheme
参考文献
Meyers; Lawson; Walker; Linderman
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5111 - 5123
反应条件
1: 83.8 percent / K2CO3 / methanol / 18 h / 23 °C 2: 48.3 percent / CrO3 / pyridine; CH2Cl2 / 1.) 0 deg C, 20 min, 2.) 23 deg C, 20 min View Scheme
参考文献
Meyers; Lawson; Walker; Linderman
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5111 - 5123
反应条件
oxalic acid chloride; dimethyl sulfoxide; triethylamine 1) in CH2Cl2, -60 deg C, 15 min., 2) -60 deg C, 5 min.; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Rosen; Taschner; Heathcock
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 3994 - 4003
反应条件
oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine 1.) CH2Cl2, -78 deg C, 2.) -78 deg C to room temp.; Multistep reaction;
参考文献
Guindon, Yvan; Yoakim, Christiane; Bernstein, Michael A.; Morton, Howard E.
Tetrahedron Letters, 1985 , vol. 26, # 9 p. 1185 - 1188
参考文献
Nakata; Saito; Oishi
Tetrahedron Letters, 1986 , vol. 27, # 52 p. 6341 - 6344
参考文献
Hanessian, Stephen; Ugolini, Antonio; Therien, Michel
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4427 - 4430
反应条件
Yield given. Multistep reaction;
参考文献
Mosset, Paul; Yadagiri, Pendri; Lumin, Sun; Capdevila, Jorge; Falck, J. R.
Tetrahedron Letters, 1986 , vol. 27, # 50 p. 6035 - 6038
反应条件
Yield given. Multistep reaction;
参考文献
Dondoni, Alessandro; Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola
Synthesis, 1988 , # 9 p. 685 - 689
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Meyers; Lawson; Walker; Linderman
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5111 - 5123
参考文献
Meyers, A.I.; Lawson, Jon P.
Tetrahedron Letters, 1982 , vol. 23, # 47 p. 4883 - 4886
