(4S)-2,2-二甲基-1,3-二氧戊环-4-乙醛合成路线 （共 25 条）
反应条件
1: 47.6 percent / SnCl2 / CH2Cl2 / 2 h / 20 °C 2: H2 / Ru[(R)-BINAP]Cl2 / methanol / 1.33 h / 20 °C / 37503 Torr View Scheme
参考文献
Tararov, Vitali I.; Koenig, Gerd; Boerner, Armin
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2633 - 2644
反应条件
1: reduction
2: 10 percent / BF3*Et2O / CHCl3 / 3 h / 25 °C
View Scheme
参考文献
Meyers, A.I.; Lawson, Jon P.
Tetrahedron Letters, 1982 , vol. 23, # 47 p. 4883 - 4886
反应条件
(i) (PhCH2O)2POH, Et3N, benzene, (ii) H2, Pd-C, EtOH; Multistep reaction;
参考文献
Tang; Tropp; Engel
Tetrahedron, 1978 , vol. 34, # 19 p. 2873 - 2878
反应条件
bromine; sodium hydrogencarbonate in water
1 h; Ambient temperature; Yield given;
参考文献
Lichtenthaler, Frieder W.; Jarglis, Pan; Lorenz, Klaus
Synthesis, 1988 , # 10 p. 790 - 792
反应条件
toluene-4-sulfonic acid
1.) CH2Cl2, overnight, 2.) CH2Cl2, 2 h; Multistep reaction;
参考文献
Bull, Steven D.; Carman, Raymond M.
Australian Journal of Chemistry, 1994 , vol. 47, # 9 p. 1661 - 1672
