5-氧代-5H-噻唑并[3,2-a]嘧啶-6-羧酸乙酯合成路线 （共 5 条）
反应条件
anhydrous trichlorobenzene
参考文献
Dunwell,D.W.; Evans,D.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2094 - 2097
反应条件
1,2,4-trichloro-benzene
参考文献
Richardson Jr.; McCarty
Journal of medicinal chemistry, 1972 , vol. 15, # 12 p. 1203 - 1206
反应条件
1: 125 °C 2: 1,2,4-trichlorobenzene View Scheme
参考文献
Richardson Jr.; McCarty
Journal of medicinal chemistry, 1972 , vol. 15, # 12 p. 1203 - 1206
反应条件
sodium hydroxide in ethanol T=20°C; Hydrolysis; 3 h;
参考文献
Peterlin-Masic, Lucija; Malesic, Mateja; Breznik, Matej; Krbavcic, Ales
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 1 p. 95 - 101
反应条件
1: 92 percent / 2 M aq. NaOH / ethanol / 3 h / 20 °C
2: oxalyl chloride; DMF / CH2Cl2 / 1.83 h / 0 - 20 °C
View Scheme
参考文献
Peterlin-Masic, Lucija; Malesic, Mateja; Breznik, Matej; Krbavcic, Ales
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 1 p. 95 - 101
