2-苄基氨基-3-氨基吡啶合成路线 （共 10 条）
反应条件
hydrogen; RaNi in methanol P=760 Torr; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 12 p. 1943 - 1947
反应条件
1: toluene / Heating 2: tin(II) chloride dihydrate / ethyl acetate / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 7 p. 1293 - 1310
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 0.5 h; Heating;
参考文献
Zecchini; Torrini; Paradisi
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 2 p. 313 - 318
反应条件
1: 80 percent / sodium carbonate / dimethylformamide / 1 h / Heating 2: H2 / RaNi / methanol / 760 Torr / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 12 p. 1943 - 1947
反应条件
1: 60 percent / pyridine / tetrahydrofuran / 0 deg C, 15 min, then room temperature, 3 h 2: 100 percent / pyridine / Ambient temperature; overnight 3: 90 percent / H2 / 5percent Pd/alumina / CH2Cl2 / 24 h 4: 90 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, # 2 p. 313 - 318
反应条件
1: 100 percent / pyridine / Ambient temperature; overnight 2: 90 percent / H2 / 5percent Pd/alumina / CH2Cl2 / 24 h 3: 90 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, # 2 p. 313 - 318
反应条件
1: 90 percent / H2 / 5percent Pd/alumina / CH2Cl2 / 24 h 2: 90 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, # 2 p. 313 - 318
反应条件
1: With triethylamine T=80°C; 2 h; 2: With hydrogenchloride; iron in ethanol; water T=80°C; 4 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 57, p. 311 - 322
反应条件
sodium tetrahydroborate; 4 A molecular sieve 1.) C6H6, reflux, 3 h; r.t., 20 h, 2.) EtOH, reflux, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 60, # 4 p. 960 - 965
反应条件
in isopropyl alcohol
Heating;
参考文献
Segelstein, Barb E.; Chenard, Bert L.; Macor, John E.; Post, Ronald J.
Tetrahedron Letters, 1993 , vol. 34, # 12 p. 1897 - 1900
