2-(4-氯苯基)氯乙烷合成路线 （共 13 条）
反应条件
thionyl chloride in dichloromethane T=0 - 20°C; 1 h;
参考文献
Nguyen, Thuy; Yang, Tianming; Go, Mei-Lin
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1830 - 1838
反应条件
tetraethylammonium chloride in acetonitrile Heating;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 44, # 11 p. 3091 - 3095
反应条件
N-chloro-succinimide in tetrahydrofuran 16 h; Ambient temperatureIrradiation;
参考文献
Collazo, Luis R.; Guziec, Frank S.; Hu, Wei-Xiao Jr.; Pankayatselvan, Ratnadevi
Tetrahedron Letters, 1994 , vol. 35, # 43 p. 7911 - 7914
反应条件
thionyl chloride in tetrahydrofuran 2 h; Heating / reflux;
参考文献
The Regents of the University of Michigan
Patent: US6342501 B1, 2002 ;
Location in patent: Scheme 2 ;
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 57, # 14 p. 3772 - 3776
反应条件
2: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 3: 95 percent / NCS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 43 p. 7911 - 7914
反应条件
1: Diazotization 2: PCl5 View Scheme
参考文献
Journal of the Chemical Society, , p. 1819
反应条件
in various solvent(s) T=100°C; CIDNP, thermolyse; Mechanism;
参考文献
Journal of Organic Chemistry, , vol. 48, # 7 p. 955 - 963
反应条件
aluminium trichloride
参考文献
Ichii,M.
Bulletin of the Chemical Society of Japan, 1972 , vol. 45, # 9 p. 2810 - 2813
反应条件
1: T=114 - 120°C; 3.16667 h; Reflux; 2: With sodium hydroxide in water T=70 - 73°C; 0.0833333 h; Product distribution / selectivity;
参考文献
ARENA PHARMACEUTICALS, INC.; DEMATTEI, John, A.; CARLOS, Marlon; CASTRO, Ryan, O.; CHUANG, Tsung-hsun; HADD, Mark, Allen; LU, Xiao-xiong; MACIAS, Mark; SHAW, Stephen, M.
Patent: WO2010/148207 A2, 2010 ;
Location in patent: Page/Page column 35 ;
