(S)-2'-氯-α-羟苯基乙酸甲酯合成路线 （共 5 条）
反应条件
trichlorophosphate; trimethyl orthoformate in toluene T=40 - 50°C;
参考文献
PORSTMANN, Frank; Meler, Thomas
Patent: US2009/105498 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; sodium formate; (1R,2R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine in water T=40°C; 1 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Ni, Yan; Li, Chun-Xiu; Zhang, Jie; Shen, Nai-Dong; Bornscheuer, Uwe T.; Xu, Jian-He
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 8 p. 1213 - 1217
反应条件
1: [VO((R,R)-1,2-bis(3,5-tBu2-salicylideneamino)cyclohexanato)] / CH2Cl2 / 20 °C 2: HCl / diethyl ether / 0 - 5 °C 3: H2O; NaHCO3 View Scheme
参考文献
Lloyd-Jones, Guy C.; Wall, Philip D.; Slaughter, Jennifer L.; Parker, Alexandra J.; Laffan, David P.
Tetrahedron, 2006 , vol. 62, # 49 p. 11402 - 11412
反应条件
C28H38N2O2; oxygen; vanadium triisopropoxide oxide in acetone T=20°C; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Yin, Lu; Jia, Xian; Li, Xing Shu; Chan, Albert S.C.
Chinese Chemical Letters, 2010 , vol. 21, # 7 p. 774 - 777
反应条件
1: HCl / diethyl ether / 0 - 5 °C 2: H2O; NaHCO3 View Scheme
参考文献
Lloyd-Jones, Guy C.; Wall, Philip D.; Slaughter, Jennifer L.; Parker, Alexandra J.; Laffan, David P.
Tetrahedron, 2006 , vol. 62, # 49 p. 11402 - 11412
