苄氧羰基-丙氨酰-苯丙氨酸甲酯合成路线 (共 23 条)
反应条件
TEA; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one in tetrahydrofuran T=20°C; 2 h;
参考文献
Li; Jiang; Ye; Fan; Romoff; Goodman
Organic letters, 1999 , vol. 1, # 1 p. 91 - 93
反应条件
triethylamine in toluene T=-14°C; 1 h;
参考文献
Joshi, Kiran; Bao, Jiang; Goldman, Alan S.; Kohn, Joachim
Journal of the American Chemical Society, 1992 , vol. 114, # 17 p. 6649 - 6652
反应条件
bislt;lt;4-(2,2-dimethyl-1,3-dioxolyl)methylgt;carbodiimide; triethylamine in N,N-dimethyl-formamide 24 h; Ambient temperature;
参考文献
Gibson, Frank S.; Park, Myung Sook; Rapoport, Henry
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7503 - 7507
反应条件
phenyl silane; tetrakis(triphenylphosphine) palladium(0) in dichloromethane 0.333333 h; Ambient temperature;
参考文献
Thieriet, Nathalie; Gomez-Martinez, Paloma; Guibe, Francois
Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2505 - 2508
反应条件
in dichloromethane T=20°C; 2 h;
参考文献
Basel, Yochai; Hassner, Alfred
Tetrahedron Letters, 2002 , vol. 43, # 14 p. 2529 - 2533
反应条件
1: 85 percent Spectr. / 4-dimethylaminopyridine; triethylamine; BOC2O / CH2Cl2 / 2.5 h / 20 °C 2: 95 percent / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Cabaret, Daniel; Wakselman, Michel
Tetrahedron Letters, 1994 , vol. 35, # 51 p. 9561 - 9564
反应条件
4-methyl-morpholine; N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate; [3H]-Strychnine in chloroform T=0 - 20°C;
参考文献
Kolesinska, Beata; Kasperowicz, Katarzyna; Sochacki, Marek; Mazur, Adam; Jankowski, Stefan; Kaminski, Zbigniew J.
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 20 - 22
反应条件
cross-linked enzyme aggregates of Alcalase T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Cusan, Claudia; Van Dooren, Theodorus J. G. M.; Moody, Harold M.; Merkx, Remco; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2399 - 2404
反应条件
4-methyl-morpholine in N,N-dimethyl-formamide
参考文献
Kawasaki; Tsuji; Hirase; Miyano; Imoto; Iwamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 3 p. 584 - 589
反应条件
in N,N-dimethyl-formamide
参考文献
Gibson, Frank S.; Park, Myung Sook; Rapoport, Henry
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7503 - 7507