苄氧羰基-丙氨酰-苯丙氨酸甲酯合成路线 （共 23 条）
反应条件
triethylamine in dichloromethane T=25°C; Yield given;
参考文献
Zhu, Yun-Fei; Fuller, William D.
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 807 - 810
反应条件
in N,N-dimethyl-formamide 15 h; Ambient temperature;
参考文献
Kawasaki, Koichi; Tsuji, Toshiki; Maeda, Misuko; Matsumoto, Tatsuya; Hirase, Katsuhiko
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1044 - 1048
反应条件
in N,N-dimethyl-formamide 15 h; Ambient temperature;
参考文献
Kawasaki, Koichi; Tsuji, Toshiki; Maeda, Misuko; Matsumoto, Tatsuya; Hirase, Katsuhiko
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1044 - 1048
反应条件
in N,N-dimethyl-formamide 15 h; Ambient temperature;
参考文献
Kawasaki, Koichi; Tsuji, Toshiki; Maeda, Misuko; Matsumoto, Tatsuya; Hirase, Katsuhiko
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1044 - 1048
反应条件
benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane 2 h; temperature: below 0 deg C;
参考文献
Matsuda, Fuyuhiko; Itoh, Shin; Hattori, Noritaka; Yanagiya, Mitsutoshi; Matsumoto, Takeshi
Tetrahedron, 1985 , vol. 41, # 18 p. 3625 - 3631
反应条件
sodium hydrogencarbonate; 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride in water T=0°C; 2 h; optical yield given as percent de;
参考文献
Zajac, Krzysztof; Kaminski, Zbigniew J.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 6 p. 725 - 728
反应条件
1: thionyl chloride / 2 h / Heating 2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 2 h / temperature: below 0 deg C View Scheme
参考文献
Hoogwater, D. A.; Peereboom, M.
Tetrahedron, 1990 , vol. 46, # 15 p. 5325 - 5332
反应条件
1: 1.) 4N NaOH / 1.) ca. 5 deg C, 15 min 2.) ethyl acetate, Et2O, 5 min 2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 2 h / temperature: below 0 deg C View Scheme
参考文献
Hoogwater, D. A.; Peereboom, M.
Tetrahedron, 1990 , vol. 46, # 15 p. 5325 - 5332
反应条件
Ambient temperature;
参考文献
Chung-hsi, Li; Yuen-hwa, Yieh; Yao, Lin; Yong-jun, Lu; Ai-hsueh, Chi; Chi-yi, Hsing
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3467 - 3470
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in 1,4-dioxane 8 h; Ambient temperature; Yield given;
参考文献
Takeda; Ayabe; Suzuki; Konda; Harigaya
Synthesis, 1991 , # 9 p. 689 - 691
