N-(4-乙基苯基)-3-氧代丁酰胺合成路线 (共 4 条)
反应条件
ammonia in chloroform; toluene
参考文献
Kawakami, Joel K.; Wetzel, John; Boteju, Lakmal W.; Konkel, Michael J.; Wan, Honghe; Noble, Stewart A.
Patent: US2003/139431 A1, 2003 ;
US 20030139431 A1
Title/Abstract Full Text Show Details
Forray, Carlos C.; Kawakami, Joel; Konkel, Michael J.; Boteju, Lakmal W.; Wetzel, John M.; Noble, Stewart A.; Wan, Honghe
Patent: US2003/176314 A1, 2003 ;
US 20030176314 A1
反应条件
triethylamine in benzene T=10°C; RefluxInert atmosphere;
参考文献
Osolodkin, Dmitry I.; Kozlovskaya, Liubov I.; Dueva, Evgenia V.; Dotsenko, Victor V.; Rogova, Yulia V.; Frolov, Konstantin A.; Krivokolysko, Sergey G.; Romanova, Ekaterina G.; Morozov, Alexey S.; Karganova, Galina G.; Palyulin, Vladimir A.; Pentkovski, Vladimir M.; Zefirov, Nikolay S.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 9 p. 869 - 874
参考文献
Forray, Carlos C.; Kawakami, Joel; Konkel, Michael J.; Boteju, Lakmal W.; Wetzel, John M.; Noble, Stewart A.; Wan, Honghe
Patent: US2003/176314 A1, 2003 ;
US 20030176314 A1
反应条件
sulfuric acid; ammonia in methanol; water
参考文献
Kawakami, Joel K.; Wetzel, John; Boteju, Lakmal W.; Konkel, Michael J.; Wan, Honghe; Noble, Stewart A.
Patent: US2003/139431 A1, 2003 ;
US 20030139431 A1