5-(5-甲基噻吩-2-基)噻吩-2-甲醛合成路线 （共 13 条）
反应条件
1: 5'-bromo-5-methyl-2,2'-bithiophene With n-butyllithium in tetrahydrofuran T=-78 - 20°C; 2.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran T=-78°C; 1.5 h;
参考文献
Melucci, Manuela; Barbarella, Giovanna; Zambianch, Massimo; Benzi, Mario; Biscarini, Fabio; Cavallini, Massimiliano; Bongini, Alessandro; Fabbroni, Serena; Mazzeo, Marco; Anni, Marco; Gigli, Giuseppe
Macromolecules, 2004 , vol. 37, # 15 p. 5692 - 5702
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl acetamide T=120°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Derridj, Fazia; Gottumukkala, Aditya L.; Djebbar, Safia; Doucet, Henri
European Journal of Inorganic Chemistry, 2008 , # 16 p. 2550 - 2559
反应条件
N,N-dimethyl-formamide; toluene; trichlorophosphate anschliessendes Behandeln mit wss. Natriumacetat-Loesung;
参考文献
Melucci, Manuela; Barbarella, Giovanna; Zambianch, Massimo; Benzi, Mario; Biscarini, Fabio; Cavallini, Massimiliano; Bongini, Alessandro; Fabbroni, Serena; Mazzeo, Marco; Anni, Marco; Gigli, Giuseppe
Macromolecules, 2004 , vol. 37, # 15 p. 5692 - 5702
反应条件
in acetonitrile 3 h; Irradiation;
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1.1: 71 percent / PdCl2*dppp; KF / toluene; methanol / 0.33 h / 80 °C / microwave irradiation 2.1: NBS / dimethylformamide 3.1: n-BuLi / tetrahydrofuran / 2.5 h / -78 - 20 °C 3.2: 74 percent / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Melucci, Manuela; Barbarella, Giovanna; Zambianch, Massimo; Benzi, Mario; Biscarini, Fabio; Cavallini, Massimiliano; Bongini, Alessandro; Fabbroni, Serena; Mazzeo, Marco; Anni, Marco; Gigli, Giuseppe
Macromolecules, 2004 , vol. 37, # 15 p. 5692 - 5702
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in methanol; toluene Suzuki coupling; Heating;
参考文献
Albano, Vincenzo Giulio; Bandini, Marco; Barbarella, Giovanna; Melucci, Manuela; Monari, Magda; Piccinelli, Fabio; Tommasi, Simona; Umani-Ronchi, Achille
Chemistry - A European Journal, 2006 , vol. 12, # 3 p. 667 - 675
反应条件
1: NaBH4 / methanol / 0.5 h / 0 °C 2: HgO, I2 / benzene / 1 h 3: PCC / CH2Cl2 4: 69 percent / acetonitrile / 3 h / Irradiation View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1: HgO, I2 / benzene / 1 h 2: PCC / CH2Cl2 3: 69 percent / acetonitrile / 3 h / Irradiation View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1: PCC / CH2Cl2 2: 69 percent / acetonitrile / 3 h / Irradiation View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
in neat (no solvent) 4 h; Irradiation;
参考文献
Krishnaswamy, N. R.; Kumar, Ch. Siva Sai Kamana; Prasanna, S.
Journal of Chemical Research, Miniprint, 1991 , # 7 p. 1801 - 1830
