反应条件
1: diethyl ether / 4 h / 0 - 2 °C 2: 79 percent / pyridine / 1.) -5 deg C, 6 h; 2.) 0 deg C, 12 h 3: 53 percent / sodium iodide, zinc dust / tetrahydrofuran / 1.) 65-70 deg C, 3 h; 2.) 20 deg C, 3 h 4: 1.) 2percent O3 in O2; 2.) sodium tetrahydroborate / 1.) cyclohexane, methanol; 2.) room temp., 15 h 5: 1.) isobutylmagnesium bromide; 2.) C5H5TiCl2 / 1.) diethyl ether, 0 deg C, 15 min; 2.) room temp., 1-1,5 h View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Ladenkova, I. M.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1987 , vol. 23, # 3 p. 365 - 368
Khimiya Prirodnykh Soedinenii, 1987 , # 3 p. 440 - 444
