(1S,6R)-1,6-二羟基环己-2,4-二烯-1-羧酸合成路线 (共 3 条)
反应条件
ammonium sulfate; manganese sulphate; potassium dihydrogenphosphate; polypropyleneglycol; (per)acetylperoxyboric acid; D-glucose; phosphoric acid; ammonia; oxygen; magnesium sulfate; copper(II) sulfate; iron(II) sulfate; anhydrous zinc sulfate; citric acid; calcium chloride in water T=30°C; Pseudomonas putida U103 presence;
参考文献
THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Patent: WO2005/112945 A2, 2005 ;
Location in patent: Page/Page column 84-85 ;
反应条件
Alcaligenes eutrophus B9 in various solvent(s) T=30°C; Title compound not separated from byproducts.;
参考文献
Myers, Andrew G.; Siegel, Dionicio R.; Buzard, Daniel J.; Charest, Mark G.
Organic Letters, 2001 , vol. 3, # 18 p. 2923 - 2926
反应条件
Ralstonia eutropha B9 Enzymatic reaction; optical yield given as percent ee;
参考文献
Adams, David R.; Aichinger, Christian; Rinner, Uwe; Hudlicky, Tomas
Synlett, 2011 , # 5 art. no. S00511ST, p. 725 - 729