5-(溴甲基)-2-(甲基硫代)嘧啶合成路线 （共 2 条）
反应条件
thionyl bromide in dichloromethane T=20°C; 2.5 h;
参考文献
MERCK SHARP and DOHME CORP.; KUDUK, Scott, D.; SCHLEGEL, Kelly-Ann; YANG, Zhi-Qiang
Patent: WO2011/84368 A1, 2011 ;
Location in patent: Page/Page column 59 ;
WO 2011/084368 A1
反应条件
1.1: diisobutylaluminium hydride / toluene; tetrahydrofuran / 2.67 h / -78 °C 1.2: -78 °C 2.1: thionyl bromide / dichloromethane / 2.5 h / 20 °C View Scheme
参考文献
MERCK SHARP and DOHME CORP.; KUDUK, Scott, D.; SCHLEGEL, Kelly-Ann; YANG, Zhi-Qiang
Patent: WO2011/84368 A1, 2011 ;
WO 2011/084368 A1
