2-(4-氟苯基)-5-苯基-1,3-恶唑合成路线 （共 20 条）
反应条件
trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene in diethyl ether; dichloromethane T=-78 - 0°C;
参考文献
Hempel, Christian; Nachtsheim, Boris J.
Synlett, 2013 , vol. 24, # 16 art. no. ST-2013-D0547-L, p. 2119 - 2123
反应条件
pyridine; oxygen; potassium carbonate; lithium bromide; copper(ll) bromide in toluene T=110°C; 11 h;
参考文献
Liu, Dongfang; Yu, Jintao; Cheng, Jiang
Tetrahedron, 2014 , vol. 70, # 6 p. 1149 - 1153
反应条件
copper(l) iodide; potassium carbonate; palladium diacetate in N,N-dimethyl-formamide T=150°C; 0.25 h; microwave irradiation;
参考文献
Besselievre, Francois; Mahuteau-Betzer, Florence; Grierson, David S.; Piguel, Sandrine
Journal of Organic Chemistry, 2008 , vol. 73, # 8 p. 3278 - 3280
反应条件
PdCl2(C3H3N2(CH3))(C3H2N2(C6H3(C3H7)2)2); lithium tert-butylate in toluene T=130°C; 18 h; Inert atmosphere;
参考文献
Shen, Xiao-Bao; Zhang, Yun; Chen, Wen-Xin; Xiao, Zheng-Kang; Hu, Ting-Ting; Shao, Li-Xiong
Organic Letters, 2014 , vol. 16, # 7 p. 1984 - 1987
反应条件
tert.-butylhydroperoxide; iodine; sodium hydrogencarbonate in N,N-dimethyl-formamide T=70°C; 10 h;
参考文献
Wan, Changfeng; Gao, Linfeng; Wang, Qiang; Zhang, Jintang; Wang, Zhiyong
Organic Letters, 2010 , vol. 12, # 17 p. 3902 - 3905
反应条件
tert.-butylhydroperoxide; iodine in dimethyl sulfoxide T=80°C;
参考文献
Jiang, Huanfeng; Huang, Huawen; Cao, Hua; Qi, Chaorong
Organic Letters, 2010 , vol. 12, # 23 p. 5561 - 5563
反应条件
oxygen; copper(l) chloride; sodium t-butanolate in N,N-dimethyl-formamide T=80°C; P=760.051 Torr; 0.333333 h;
参考文献
Yang, Fanzhi; Xu, Zhaoqing; Wang, Zhe; Yu, Zhengkun; Wang, Rui
Chemistry - A European Journal, 2011 , vol. 17, # 23 p. 6321 - 6325
反应条件
iodine in dimethyl sulfoxide T=100°C;
参考文献
Gao, Qing-He; Fei, Zhuan; Zhu, Yan-Ping; Lian, Mi; Jia, Feng-Cheng; Liu, Mei-Cai; She, Neng-Fang; Wu, An-Xin
Tetrahedron, 2013 , vol. 69, # 1 p. 22 - 28
反应条件
pyridine; oxygen; potassium carbonate; copper(I) bromide in toluene T=80°C; P=760.051 Torr; 16 h; Schlenk technique;
参考文献
Xu, Zejun; Zhang, Chun; Jiao, Ning
Angewandte Chemie - International Edition, 2012 , vol. 51, # 45 p. 11367 - 11370
Angew. Chem.
反应条件
iodine; potassium carbonate in N,N-dimethyl-formamide T=80°C; 4 h;
参考文献
Gao, Wen-Chao; Wang, Ruo-Lin; Zhang, Chi
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 41 p. 7123 - 7128
