1-苯基-4-戊烯-1-酮合成路线 （共 116 条）
反应条件
1: NaHMDS / tetrahydrofuran / -78 - 20 °C
2: Et3N; DMAP / CH2Cl2 / 4 h / 20 °C
3: 78 percent / LiEt3BH; Te / tetrahydrofuran / 0.42 h / 20 °C
View Scheme
参考文献
Avilov, Dmitry V.; Malusare, Mahesh G.; Arslancan, Engin; Dittmer, Donald C.
Organic Letters, 2004 , vol. 6, # 13 p. 2225 - 2228
反应条件
1: 73 percent / DBU / benzene / Ambient temperature
2: 94 percent / HEH / RuCl2(bpy)3 / pyridine / Ambient temperature; Irradiation
View Scheme
参考文献
Fujii, Masayuki; Nakamura, Kaoru; Mekata, Hidevuki; Oka, Shinzaburo; Ohno, Atsuyoshi
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 495 - 500
反应条件
in diethyl ether
T=20°C; Inert atmosphere;
参考文献
Brenzovich Jr., William E.; Benitez, Diego; Lackner, Aaron D.; Shunatona, Hunter P.; Tkatchouk, Ekaterina; Goddard III, William A.; Toste, F. Dean
Angewandte Chemie - International Edition, 2010 , vol. 49, # 32 p. 5519 - 5522
反应条件
in dichloromethane
0.166667 h; Ambient temperature;
参考文献
Zhdankin, Viktor V.; Mullikin, Michelle; Tykwinski, Rik; Berglund, Bruce; Caple, Ronald; et al.
Journal of Organic Chemistry, 1989 , vol. 54, # 11 p. 2605 - 2608
反应条件
nickel; acetic acid in n-heptane
参考文献
Boivin, Jean; Schiano, Anne-Marie; Zard, Samir Z.; Zhang, Haiwen
Tetrahedron Letters, 1999 , vol. 40, # 24 p. 4531 - 4534
反应条件
1: 2-propenylmagnesium bromide in tetrahydrofuran
8 h; Heating;
2: α-bromoacetophenone With 2,2'-azo-bisisobutyronitrile in benzene
12 h; Further stages.;
参考文献
Enholm, Eric J.; Gallagher, Maria E.; Moran, Kelley M.; Lombardi, Jennifer S.; Schulte II, James P.
Organic Letters, 1999 , vol. 1, # 5 p. 689 - 691
反应条件
cesium fluoride in tetrahydrofuran
15 h; Ambient temperature;
参考文献
Fiorenza, Mariella; Mordini, Alessandro; Papaleo, Sandro; Pastorelli, Stefania; Ricci, Alfredo
Tetrahedron Letters, 1985 , vol. 26, # 6 p. 787 - 788
反应条件
1: 80 percent / NaH / tetrahydrofuran / 20 °C
2: 78 percent / LiBr / H2O; dimethylformamide / 72 h / 195 - 200 °C
View Scheme
参考文献
Hok, Saphon; Schore, Neil E.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1736 - 1738
反应条件
1: 1.) Mg / 1.) diethyl ether; 2.) diethyl ether, reflux, 1h
2: pyridinium chlorochromate (PCC) / CH2Cl2 / 3 h / Heating
View Scheme
参考文献
Tokuda, Masao; Yamada, Yasufumi; Takagi, Toshiya; Suginome, Hiroshi; Furusaki, Akio
Tetrahedron, 1987 , vol. 43, # 2 p. 281 - 296
反应条件
2,4-di-Nitrobenzene; 2,2'-azo-bisisobutyronitrile in benzene
T=61°C; 53 h; Product distributionMechanism;
参考文献
Li, Xianfeng; Chen, Jian J.; Tanner, Dennis D.
Journal of Organic Chemistry, 1996 , vol. 61, # 13 p. 4314 - 4318
