(S)-1-苄基-3-乙基哌嗪合成路线 （共 4 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=65°C; 17 h; 2: With water in tetrahydrofuran T=0°C;
参考文献
AMR TECHNOLOGY, INC.
Patent: US2008/255114 A1, 2008 ;
Location in patent: Page/Page column 28 ;
反应条件
1: DCC / CH2Cl2 / 18 h 2: 1.) aq. HCl, 2.) aq. NaHCO3 / 1.) CHCl3 3: LiAlH4 / tetrahydrofuran / 15 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1345 - 1348
反应条件
1: CH2Cl2 / 2 h 2: H2 / 10percent Pd/C / methanol / 16 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1345 - 1348
反应条件
in dichloromethane
2 h;
参考文献
Eli Lilly and Company
Patent: US6638936 B1, 2003 ;
