1-BOC-3,3-二甲基-4-氧代哌啶合成路线 （共 12 条）
反应条件
1: With ammonium acetate in methanol
T=20°C; 3 h; Inert atmosphere;
2: With sodium cyanoborohydride in methanol
T=0 - 20°C; 22.0833 h;
3: With water
0.333333 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; WROBLESKI, Stephen T.; DAS, Jagabandhu; DUAN, Jingwu; GUO, Junqing; HYNES, John; JIANG, Bin; KEMPSON, James; LIN, Shuqun; LU, Zhonghui; PITTS, William J.; SPERGEL, Steven H.; WU, Hong; YANG, Bingwei Vera
Patent: WO2012/125893 A1, 2012 ;
Location in patent: Page/Page column 138 ;
WO 2012/125893 A1
参考文献
Austin, Nigel E.; Hadley, Michael S.; Harling, John D.; Harrington, Frank P.; Macdonald, Gregor J.; Mitchell, Darren J.; Riley, Graham J.; Stean, Tania O.; Stemp, Geoffrey; Stratton, Sharon C.; Thompson, Mervyn; Upton, Neil
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1627 - 1629
