2-乙基-3-氧代戊酸甲酯合成路线 (共 8 条)
反应条件
potassium carbonate in tetrahydrofuran Heating;
参考文献
Jones, Simon M.; Urch, Jonathan E.; Kaiser, Marcel; Brun, Reto; Harwood, John L.; Berry, Colin; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5932 - 5941
反应条件
potassium carbonate in tetrahydrofuran Heating;
参考文献
Jones, Simon M.; Urch, Jonathan E.; Brun, Reto; Harwood, John L.; Berry, Colin; Gilbert, Ian H.
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 4 p. 683 - 692
反应条件
1: CH2Cl2 View Scheme
参考文献
Moriconi,E.J.; Shimakawa,Y.
Journal of Organic Chemistry, 1972 , vol. 37, p. 196 - 207
反应条件
methanol; sodium methylate anschliessend mit Aethyljodid;
参考文献
Buechi et al.
Helvetica Chimica Acta, 1953 , vol. 36, p. 1402,1408
参考文献
Moriconi,E.J.; Shimakawa,Y.
Journal of Organic Chemistry, 1972 , vol. 37, p. 196 - 207
反应条件
(i) (irradiation), Et2O, (ii) /BRN= 102415/; Multistep reaction;
参考文献
Korobitsyna,I.K.; Nikolaev,V.A.
Zhurnal Organicheskoi Khimii, 1976 , vol. 12, p. 1251 - 1260,1252 - 1260
反应条件
1: 49 percent / NaOAc / xylene / 5.5 h / Heating 2: 36 percent / NaOMe / methanol; toluene / 2 h / Heating View Scheme
参考文献
Tice; Bryman
Tetrahedron, 2001 , vol. 57, # 14 p. 2689 - 2700
反应条件
1: PyBr3; AcOH / 20 °C
2: 33 percent / aq. KOH / 15 h / 20 °C
View Scheme
参考文献
Jones, Simon M.; Urch, Jonathan E.; Kaiser, Marcel; Brun, Reto; Harwood, John L.; Berry, Colin; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5932 - 5941