2-羟基-1H-吡咯并[3,2-b]吡啶-3-甲腈合成路线 (共 4 条)
反应条件
in xylene 16 h; Heating / reflux;
参考文献
Turner, Sean C.; White, Tammie K.; Carroll, William A.
Patent: US2004/192697 A1, 2004 ;
Location in patent: Page 17 ;
反应条件
1.1: 74 percent / KOtBu / propan-2-ol / 6.5 h / -20 - 82 °C 2.1: 99 percent / H2 / Pd/C / ethanol / 3 h / 2585.74 Torr 3.1: xylene / 20 h / Heating 3.2: aq. NaOH 3.3: CO2 / H2O View Scheme
参考文献
Turner, Sean C.; Carroll, William A.; White, Tammie K.; Gopalakrishnan, Murali; Coghlan, Michael J.; Shieh, Char-Chang; Zhang, Xu-Feng; Parihar, Ashutosh S.; Buckner, Steven A.; Milicic, Ivan; Sullivan, James P.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 12 p. 2003 - 2007
反应条件
1.1: 99 percent / H2 / Pd/C / ethanol / 3 h / 2585.74 Torr 2.1: xylene / 20 h / Heating 2.2: aq. NaOH 2.3: CO2 / H2O View Scheme
参考文献
Turner, Sean C.; Carroll, William A.; White, Tammie K.; Gopalakrishnan, Murali; Coghlan, Michael J.; Shieh, Char-Chang; Zhang, Xu-Feng; Parihar, Ashutosh S.; Buckner, Steven A.; Milicic, Ivan; Sullivan, James P.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 12 p. 2003 - 2007
反应条件
trichlorophosphate
T=105°C; 2 h;
参考文献
Turner, Sean C.; White, Tammie K.; Carroll, William A.
Patent: US2004/192697 A1, 2004 ;
Location in patent: Page 17 ;