1,3-二氢-2H-吡咯并[3,2-b]吡啶-2-酮合成路线 （共 7 条）
反应条件
hydrogenchloride in diethyl ether
参考文献
SmithKline Beecham Corporation
Patent: US6624171 B1, 2003 ;
US 6624171 B1
反应条件
in dichloromethane; ethyl acetate
参考文献
Zeneca Limited
Patent: US6294532 B1, 2001 ;
反应条件
1: dimethylsulfoxide 2: aq. LiCl / dimethylsulfoxide 3: H2 / Pd/C / ethanol / 2068.59 Torr 4: HCl / diethyl ether View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 4 p. 953 - 957
反应条件
1: aq. LiCl / dimethylsulfoxide 2: H2 / Pd/C / ethanol / 2068.59 Torr 3: HCl / diethyl ether View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 4 p. 953 - 957
反应条件
1: H2 / Pd/C / ethanol / 2068.59 Torr 2: HCl / diethyl ether View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 4 p. 953 - 957
反应条件
1: 80 percent / hydrogen / 10percent palladised charcoal / ethanol / 4 h 2: 74 percent / ethanol / 1.) 70 deg C, 1 h, 2.) reflux, 2 min View Scheme
参考文献
Synthetic Communications, , vol. 11, # 9 p. 743 - 750
反应条件
in ethanol 1.) 70 deg C, 1 h, 2.) reflux, 2 min;
参考文献
Daisley, R. W.; Hanbali, J. R.
Synthetic Communications, 1981 , vol. 11, # 9 p. 743 - 750
