5,10-二氢茚并[3,2-b]吲哚合成路线 （共 24 条）
反应条件
sodium cyanoborohydride in acetic acid 3 h; below 18 deg C;
参考文献
Brown, David W.; Graupner, Paul R.; Sainsbury, Malcolm; Shertzer, Howard G.
Tetrahedron, 1991 , vol. 47, # 25 p. 4383 - 4408
反应条件
air; sodium hydride in dimethyl sulfoxide
T=40 - 50°C; 96 h;
参考文献
Graupner, Paul R.; Mahon, Mary F.; Ninan, Aleyamma; Sainsbury, Malcolm; Shertzer, Howard G.
Tetrahedron Letters, 1995 , vol. 36, # 32 p. 5827 - 5830
反应条件
1: 1) 1.6M n-BuLi / 1) hexane, THF, RT, 1 h, 2) THF, overnight, RT
2: 1) 1.6M n-BuLi / 1) hexane, THF, RT, 0.5 h, 2) THF, 3 h, RT
3: KF, 18-crown-6 / tetrahydrofuran / 4 h / Ambient temperature
View Scheme
参考文献
Abraham, Tonson
Monatshefte fuer Chemie, 1989 , vol. 120, p. 117 - 126
反应条件
1: 1) 1.6M n-BuLi / 1) hexane, THF, RT, 1 h, 2) THF, overnight, RT
2: 1) 1.6M n-BuLi / 1) hexane, THF, RT, 0.5 h, 2) THF, 3 h, RT
3: KF, 18-crown-6 / tetrahydrofuran / 4 h / Ambient temperature
View Scheme
参考文献
Abraham, Tonson
Monatshefte fuer Chemie, 1989 , vol. 120, p. 117 - 126
