4-氯-N-(6-氯吡啶-3-基)苯甲酰胺合成路线 (共 3 条)
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C;
参考文献
Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484
反应条件
1: palladium 10 on activated carbon; hydrogen / dichloromethane 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C View Scheme
参考文献
Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484
反应条件
1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C View Scheme
参考文献
Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484