N-苄基-3-(叔丁基二甲基锡氧基甲基)-4-哌啶酮合成路线 （共 2 条）
反应条件
1H-imidazole in DMF (N,N-dimethyl-formamide) T=20°C; 16 h;
参考文献
ELI LILLY AND COMPANY
Patent: EP1204659 B1, 2003 ;
Location in patent: Page/Page column 28 ;
反应条件
1: 1-Benzyl-4-piperidon-3-carbonsaeuremethylester With 1H-imidazole; tert-butyldimethylsilyl chloride in N,N-dimethyl-formamide T=20°C; 0.5 h; 2: With lithium aluminium tetrahydride in diethyl ether T=0°C; 1.5 h; 3: tert-butyldimethylsilyl chloride With 1H-imidazole; methanol more than 3 stages;
参考文献
EP1726590 A1, ;
Page/Page column 59 ;
