(R)-(+)-1-辛炔-3-醇合成路线 （共 41 条）
反应条件
(-)-(S)-BINAL-H in tetrahydrofuran 1.) -100 deg C, 1 h; 2.) -78 deg C, 2 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 106, # 22 p. 6717 - 6725
反应条件
lithium aluminium tetrahydride; (-)-N-methylephedrine in diethyl ether T=-15°C; 0.25 h;
参考文献
Bulletin de la Societe Chimique de France, , # 1 p. 165 - 173
反应条件
lithium diisopropyl amide in tetrahydrofuran; hexane T=0°C; 0.5 h;
参考文献
Tetrahedron Letters, , vol. 30, # 50 p. 7083 - 7086
反应条件
sodium hydride in tetrahydrofuran T=0°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 34, # 41 p. 6587 - 6590
反应条件
vinyl acetate; Novozym 435 in hexane T=60°C; Enzymatic reaction; optical yield given as percent ee;
参考文献
Chemistry - A European Journal, , vol. 15, # 12 p. 2751 - 2754
反应条件
CAL-B in toluene T=20°C; 16 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 12, # 20 p. 4702 - 4704
反应条件
1: With PISA1 sulfatase; water in aq. buffer T=30°C; pH=8; 24 h; Enzymatic reaction; 2: With recombinant N-terminally strep-tag Pseudomonas aeruginosa arylsulfatase in aq. buffer T=30°C; pH=8; 24 h; enantioselective reaction;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 11 p. 3277 - 3279
Angew. Chem., , vol. 125, # 11 p. 3359 - 3361,3
反应条件
sodium hydride in tetrahydrofuran T=0°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 640 - 647
反应条件
pyridinium p-toluenesulfonate in isopropyl alcohol
参考文献
Tetrahedron Letters, , vol. 30, # 50 p. 7083 - 7086
反应条件
potassium hydroxide; tetra-(n-butyl)ammonium iodide in hexane; water T=50°C; 3 h; ee>99percent;
参考文献
Tetrahedron Letters, , vol. 28, # 18 p. 2033 - 2036
