(R)-(+)-1-辛炔-3-醇合成路线 （共 41 条）
反应条件
sodium sulfate; Birman's catalyst in chloroform T=0°C; 6 h;
参考文献
Organic Letters, , vol. 8, # 21 p. 4859 - 4861
反应条件
1: 91 percent / TiCl4 / CH2Cl2 / -78 °C 2: 97 percent / PCC 3: aq. KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 105, # 9 p. 2904 - 2905
反应条件
1: 97 percent / PCC 2: aq. KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 105, # 9 p. 2904 - 2905
反应条件
potassium hydroxide in methanol Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 105, # 9 p. 2904 - 2905
反应条件
pyridine in tetrahydrofuran T=10°C; 0.25 h;
参考文献
Synthetic Communications, , vol. 21, # 6 p. 833 - 839
反应条件
1: With tetrachloromethane; sodium hydrogencarbonate; triphenylphosphine Heating; 2: With lithium diisopropyl amide in tetrahydrofuran T=-30 - 20°C;
参考文献
Tetrahedron Letters, , vol. 42, # 35 p. 6057 - 6060
反应条件
1: nBu4NF / tetrahydrofuran / 0 °C / ee>99percent 2: 50percent KOH / nBu4NI / hexane; H2O / 3 h / 50 °C / ee>99percent View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 18 p. 2033 - 2036
反应条件
1: TBHP, L-(+)-DIPT, Ti(O-iPr)4 / CH2Cl2 / -20 °C / ee>99percent 2: Br2 / CH2Cl2 3: nBu4NF / tetrahydrofuran / 0 °C / ee>99percent 4: 50percent KOH / nBu4NI / hexane; H2O / 3 h / 50 °C / ee>99percent View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 18 p. 2033 - 2036
反应条件
1: Br2 / CH2Cl2 2: nBu4NF / tetrahydrofuran / 0 °C / ee>99percent 3: 50percent KOH / nBu4NI / hexane; H2O / 3 h / 50 °C / ee>99percent View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 18 p. 2033 - 2036
反应条件
immobilized Candida antarctica Lipase B in di-isopropyl ether T=25°C; Enzymatic reaction;
参考文献
Journal of Organic Chemistry, , vol. 69, # 21 p. 7108 - 7113
