(R)-(+)-1-辛炔-3-醇合成路线 （共 41 条）
反应条件
tetrabutyl ammonium fluoride desilylation;
参考文献
Journal of the American Chemical Society, , vol. 121, # 33 p. 7600 - 7605
反应条件
zinc trifluoromethanesulfonate; (+)-N-methylephedrine; N-ethyl-N,N-diisopropylamine in toluene T=23°C; 168 h;
参考文献
Helvetica Chimica Acta, , vol. 84, # 4 p. 964 - 971
反应条件
Candida antarctica lipase in di-isopropyl ether T=25°C; 2 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5351 - 5356
反应条件
1.1: LDA / tetrahydrofuran; hexane / 0.17 h / -100 °C 1.2: 25 percent / tetrahydrofuran / 0.33 h / -100 °C 2.1: 64 percent / NaH / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 640 - 647
反应条件
1: CBS 2: TBAF View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 33 p. 7600 - 7605
反应条件
His-tagged Pseudomonas sp. metallo-β-lactamase-type alkylsulfatase Pisa1; water; tris(hydroxymethyl)methylamine hydrochloride T=30°C; pH=8.2; 6 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Organic Letters, , vol. 13, # 16 p. 4296 - 4299
反应条件
1: 93 percent / LiNH2 / liquid ammonia; tetrahydrofuran / 1 h / -78 °C 2: 92 percent / PPTS / propan-2-ol View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 50 p. 7083 - 7086
反应条件
1: 95 percent / LiNH2 / liquid ammonia; tetrahydrofuran / -78 °C 2: n-Bu4NF View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 50 p. 7083 - 7086
反应条件
10M acid-treated K10 Montmorillonite T=40°C; 20 h; optical yield given as percent ee;
参考文献
New Journal of Chemistry, , vol. 34, # 3 p. 398 - 402
反应条件
PISA1 sulfatase; water in aq. buffer pH=8; 24 h; Enzymatic reaction; enantioselective reaction;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 11 p. 3277 - 3279
Angew. Chem., , vol. 125, # 11 p. 3359 - 3361,3
