(S)-1-辛炔-3-醇合成路线 （共 46 条）
反应条件
9-borabicyclo[3.3.1]nonane dimer; nopol benzyl ether; propionaldehyde Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Midland, M. Mark; Tramontano, Alfonso; Kazubski, Aleksander; Graham, Richard S.; Tsai, David J. S.; Cardin, Daniel B.
Tetrahedron, 1984 , vol. 40, # 8 p. 1371 - 1380
反应条件
1.1: LDA / tetrahydrofuran; hexane / 0.17 h / -100 °C 1.2: 68 percent / tetrahydrofuran / 0.33 h / -100 °C 2.1: 65 percent / NaH / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 640 - 647
反应条件
1: K2CO3; Na2SO4; MeOH 2: CCl4; Ph3P; NaHCO3 / Heating 3: LDA / tetrahydrofuran / -70 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 6 p. 823 - 826
反应条件
1: 62 percent / CH2Cl2 / 0.5 h / Heating 2: 88 percent / 10percent NaOH / 1 h / 60 °C View Scheme
参考文献
Tetrahedron, , vol. 43, # 9 p. 2013 - 2020
反应条件
1: 86 percent / triphenylphosphine, CCl4 / 10 h / Heating 2: 1.) n-BuLi, hexamethylphosphoric triamide (HMPA) / 1.) hexane, THF, -35 deg C, 8 min View Scheme
参考文献
Heterocycles, , vol. 31, # 9 p. 1721 - 1725
反应条件
phosphate buffer; lyophilized yeast in water
参考文献
Tetrahedron, , vol. 43, # 24 p. 5791 - 5796
反应条件
1: acetone / Ambient temperature; phosphate buffer, pH 7, Lipase PPL 2: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemistry Letters, , # 1 p. 107 - 110
反应条件
1: 35 percent / tetrahydrofuran / Ambient temperature; phosphate buffer, pH 7, Lipase Amano PS 2: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemistry Letters, , # 1 p. 107 - 110
反应条件
1: 83 percent / LiCl / dimethylformamide / 3.5 h / 60 °C 2: 1.) n-BuLi, hexamethylphosphoric triamide (HMPA) / 1.) hexane, THF, -35 deg C, 8 min View Scheme
参考文献
Heterocycles, , vol. 31, # 9 p. 1721 - 1725
反应条件
NB-Enantrane 48 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 14 p. 2814 - 2816
