[(2R,3S,4R,5R)-5-(6-氨基嘌呤-9-基)-3,4-二羟基四氢呋喃-2-基]甲基[(2R,3S,4R,5R)-5-(2,4-二氧代嘧啶-1-基)-4-羟基-2-(羟基甲基)四氢呋喃-3-基]磷酸氢酯合成路线 （共 14 条）
反应条件
1: 74 percent / cesium fluoride / acetonitrile / Ambient temperature View Scheme
参考文献
Takaku, Hiroshi; Nomoto, Tadaaki; Murata, Mitsuho; Hata, Tsujiaki
Chemistry Letters, 1980 , p. 1419 - 1422
反应条件
1: 74 percent / cesium fluoride / acetonitrile / Ambient temperature View Scheme
参考文献
Takaku, Hiroshi; Nomoto, Tadaaki; Murata, Mitsuho; Hata, Tsujiaki
Chemistry Letters, 1980 , p. 1419 - 1422
反应条件
1: 31 percent / 2,6-lutidine / tetrahydrofuran / 0.33 h / 0 °C View Scheme
参考文献
Ozaki, Hiroaki; Nakamoto, Akio; Shimidzu, Takeo
Chemistry Letters, 1990 , # 6 p. 959 - 962
反应条件
1.1: bis(2-pyridinyl)-disulfide; triethylamine; triphenylphosphine / dimethyl sulfoxide; N,N-dimethyl-formamide / 3 h 1.2: 2 h 2.1: Na(+)-montmorillonite / 1 h / 24 °C 2.2: 24 °C View Scheme
参考文献
Joshi, Prakash C.; Aldersley, Michael F.; Zagorevskii, Dmitri V.; Ferris, James P.
Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 7 p. 536 - 566
反应条件
1: 3N-(D-1-ribose)-uracil With Na(+)-montmorillonite T=24°C; 1 h; 2: D-ImpA T=24°C;
参考文献
Joshi, Prakash C.; Aldersley, Michael F.; Zagorevskii, Dmitri V.; Ferris, James P.
Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 7 p. 536 - 566
反应条件
1,4-dioxane; tributyl-amine; phenylphosphorochloridate Erwaermen des Reaktionsprodukts mit wss.NH3;
参考文献
Michelson
Journal of the Chemical Society, 1959 , p. 3655,3664,3666
Biochemical Preparations, 1963 , vol. 10, p. 131
反应条件
(Zn(2+))3(1,3,5-tris[(1,5,9-triazacyclododecan-3-yl)oxymethyl]benzene)(6+) in water T=35°C; pH=7.5; aq. buffer; Kinetics; regioselective reaction;
参考文献
Laine, Maarit; Ketomaeki, Kaisa; Poijaervi-Virta, Paeivi; Loennberg, Harri
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 13 p. 2780 - 2787
反应条件
Yield given. Multistep reaction;
参考文献
Takaku, Hiroshi; Nomoto, Tadaaki; Murata, Mitsuho; Hata, Tsujiaki
Chemistry Letters, 1980 , p. 1419 - 1422
反应条件
Yield given. Multistep reaction;
参考文献
Ozaki, Hiroaki; Nakamoto, Akio; Shimidzu, Takeo
Chemistry Letters, 1990 , # 6 p. 959 - 962
反应条件
zinc dinitrate; sodium nitrate; HEPES buffer in water T=90.1°C; Rate constant;
参考文献
Wang, Qi; Loennberg, Harri
Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10716 - 10728
